HIRANO LAB RIEC/AIMR, Tohoku University

Nano-Bio Hybrid Molecular Devices Laboratory


Professor Ayumi Hirano-Iwata

Research field

Bioelectronics, nanobiotechnology, biosensors


Japan Society for Applied Physics, Surface Science Society of Japan,
 Chemical Society of Japan, Japan Society for Analytical Chemistry,
  American Chemical Society, Japanese Pharmacological Society

ProfessorAyumi Hirano-Iwata


1993年BA Department of Chemistry, School of Science, The University of Tokyo
1998年PhD Graduate School of Science, The University of Tokyo
1998年JSPS Research Fellow College of Humanities and Sciences, Nihon University
2000年Research Assistant College of Humanities and Sciences, Nihon University
2003年JSPS Research Fellow MRC National Institute for Medical Reserach, UK
2006年Assistant Professor RIEC, Tohoku University
2008年Associate Professor Grad. School of Biomedical Engineering, Tohoku University
2016年 Professor AIMR/RIEC, Tohoku University


Ongoing projects

  • Reconstitution and aplication of biological functions on chips
  • Novel electronic devices based on biomolecules


Artificial bilayer lipid membranes, nanostructures, neural signal transmission

Selected publications

  • An electrically resistive sheet of glial cells for amplifying signals of neuronal extracellular recordings.
    R. Matsumura, H. Yamamoto, M. Niwano, and A. Hirano-Iwata
    Appl. Phys. Lett., 108, 023701 (2016).
  • Reconstitution of human ether-a-go-go-related gene channels in microfabricated silicon chips.
    A. Oshima, A. Hirano-Iwata, H. Mozumi, Y. Ishinari, Y. Kimura, and M. Niwano
    Anal. Chem. 85, 4363-4369 (2013).
  • Free-standing lipid bilayers in silicon chips—Membrane stabilization based on microfabricated apertures with a nanometer-scale smoothness.
    A. Hirano-Iwata, K. Aoto, A. Oshima, T. Taira, R. Yamaguchi, Y. Kimura, and M. Niwano
    Langmuir 26, 1949-1952 (2010).
  • Label-free detection of protein-protein interactions at the GaAs/water interface through surface infrared spectroscopy: Discrimination between specific and nonspecific interactions by using secondary structure analysis.
    K. Onodera, A. Hirano-Iwata, K. Miyamoto, Y. Kimura, M. Kataoka, Y. Shinohara, and M. Niwano
    Langmuir 23, 12287-12292 (2007).
  • A single-channel sensor based on gramicidin controlled by molecular recognition at bilayer lipid membranes containing receptor.
    A. Hirano, M. Wakabayashi, Y. Matsuno, and M. Sugawara
    Biosens. Bioelectron. 18, 973-983 (2003).


2005Japan Society for Analytical Chemistry Encouragement Prize
2015Minoru Ishida Foundation Research Encouragement Prize
2015RIEC Award for Tohoku University Researchers


2002Secretary Japan Society for Analytical Chemistry, Kanto Branch
2007Secretary Japan Society for Analytical Chemistry, Tohoku Branch
2011-13Secretary Japan Society for Applied Physics M&BE
2012Vice Chair International Symposium ISSS-7 Program Commitee
2013-Vice Chair Surface Science Society of Japan, Division of Soft-Nanotechnology
2013-Program Advisor JST CREST/PRESTO Program "Hyper-nano-space design toward innovative functionality"