HIRANO LAB RIEC/AIMR, Tohoku University

Nano-Bio Hybrid Molecular Devices Laboratory



  • 赤外分光「その場」解析法によるバイオ計測.
    庭野道夫, 平野愛弓
    分析化学 64, 793-800 (2015).
  • すごいぞ!身のまわりの表面科学(日本表面科学会編).
    平野愛弓 (分担執筆)
    講談社ブルーバックス B-1940 (2015).
  • Photopatterning proteins and cells in aqueous environment using TiO2 photocatalysis.
    H. Yamamoto, T. Demura, K. Sekine, S. Kono, M. Niwano, A. Hirano-Iwata, T. Tanii
    J. Vis. Exp. 104, e53045 (2015).
  • Molecular doping of regioregular poly(3-hexylthiophene) layers by 2,3,5,6-tetrafluoro-7,7,8,8-tetracyanoquinodimethane investigated by infrared spectroscopy and electrical measurements.
    D. Tadaki, T. Ma, J. Zhang, S. Iino, A. Hirano-Iwata, Y. Kimura, M. Niwano
    Jpn. J. Appl. Phys. 54, 091602 (2015).
  • Micro- and Nano-Technologies for Lipid Bilayer-Based Ion-Channel Functional Assays.
    A. Hirano-Iwata, Y. Ishinari, H. Yamamoto, M. Niwano
    Chem. Asian J. 10, 1266-1274 (2015). (Review)
  • Annealing-induced chemical and structural changes in tri-iodide and mixed-halide organometal perovskite layers.
    T. Ma, M. Cagnoni, D. Tadaki, A. Hirano-Iwata, M. Niwano
    J. Mater. Chem. A 3, 14195-14201 (2015).


  • Real-time monitoring of extracellular L-glutamate levels released by high-frequency stimulation at region CA1 of hippocampal slices with a glass capillary-based L-glutamate sensor.
    Y. Ikegami, S. Hozumi, A. Shoji, A. Hirano-Iwata, T. Bliss, M. Sugawara
    Sens. Bio-Sens. Res. 2, 31-37 (2014).
  • シリコン微細加工で創るイオンチャネルチップ.
    平野愛弓, 石成 裕, 木村康男, 庭野道夫
    表面科学 35, 438-442 (2014).
  • Interference between field excitatory postsynaptic potentials and simultaneously recorded chronoamperometric L-glutamate currents in mouse hippocampal slices.
    A. Hirano-Iwata, R. Matsumura, R. Tezuka, M. Niwano, T.V.P. Bliss, M. Sugawara
    Electrochem. Commun. 45, 1-4 (2014).


  • Reconstitution of human ether-a-go-go-related gene channels in microfabricated silicon chips.
    A. Oshima, A. Hirano-Iwata, H. Mozumi, Y. Ishinari, Y. Kimura, M. Niwano
    Anal. Chem. 85, 4363-4369 (2013).
  • Label-free and real time monitoring of adipocyte differentiation by surface infrared spectroscopy.
    Y. Aonuma, Y. Kondo, A. Hirano-Iwata, A. Nishikawa, Y. Shinohara, H. Iwata, Y. Kimura, M. Niwano
    Sens. Actuators B Chem. 176, 1176-1182 (2013).


  • Lipid bilayer array for simultaneous recording of ion channel activities.
    A. Hirano-Iwata, T. Nasu, A. Oshima, Y. Kimura, M. Niwano
    Appl. Phys. Lett. 101, 023702 (2012).
  • Mechanically stable lipid bilayers in teflon-coated silicon chips for single-channel.
    A. Oshima, A. Hirano-Iwata, T. Nasu, Y. Kimura, M. Niwano
    Micro and Nanosystems 4, 2-7 (2012).
  • ナノ・マイクロ加工に基づく人工細胞膜センサの研究.
    平野愛弓, 大嶋 梓, 木村康男, 庭野道夫
    応用物理 81, 143-146 (2012).


  • 微細加工で創る人工細胞膜センサ―イオンチャネルチップの実現へ向けて―.
    未来材料 11, 40-44 (2011).
  • In situ modification of lipid-loaded MCM-41 channels with bovine serum albumin at a planar lipid bilayer for biosensing.
    K. Nozawa, A. Oshima, T. Nasu, A. Shoji, A. Hirano-Iwata, M. Niwano, M. Sugawara
    Sens. Actuators B Chem. 160, 139-144 (2011).
  • Real-time monitoring of mitochondrial adenosine 5’-triphosphate synthesis and hydrolysis by surface infrared spectroscopy.
    R. Yamaguchi, A. Hirano-Iwata, Y. Aonuma, Y. Yoshimura, Y. Shinohara, Y. Kimura, M. Niwano
    Appl. Phys. Lett. 98, 133703 (2011).
  • Simultaneous monitoring of excitatory postsynaptic potentials and extracellular L-glutamate in mouse hippocampal slices.
    S. Hozumi, K. Ikezawa, A. Shoji, A. Hirano-Iwata, T. Bliss, M. Sugawara
    Biosens. Bioelectron. 26, 2975-2980 (2011).