Nano-Bio Hybrid Molecular Devices

ProfessorAyumi HiranoNano-Bio Hybrid Molecular Device
Assistant ProfessorDaisuke Tadaki
Assistant ProfessorMaki Komiya

Research Activities

Our research activities focus on development of highly sophisticated molecular-scale nanodevices through the combination of well-established microfabrication techniques and various soft materials, such as biomaterials and organic materials. We are working on medical bioelectronics where we try to apply semiconductor micro- and nano-fabrication techniques to development of a sensor platform for drug screening, organic electronics where we try to develop various sensors based on organic materials, and bioelectronics where we try to construct artificial neuronal circuits as a model system for understanding brain functions. These devices can combine with information systems, leading to realization of a new technology for health-conscious society.

Nano-Bio Hybrid Molecular Devices|Hirano Group

We are working on development of novel devices based on the combination of nanotechnology and biomaterials that have highly sophisticated functions. In particular, we are aiming to reconstitute artificial cell membrane structures as a platform for high-throughput screening of new drug candidates. We are also applying such fabrication technology to brain research, and are investigating construction of a brain model system by utilizing living neuronal cells as fundamental elements. In addition, we are developing bio and organic devices with novel functions. Through the evaluation of their working principles, we are aiming to create novel electronic devices that do not solely rely on conventional semiconductor materials.

Research topics

  • Development of artificial cell membrane sensors and their medical applications
  • Fabrication of nanostructures and their biosensor applications
  • Construction of artificial neuronal networks based on cultured neurons
  • Modelling of biosystems and neuronal circuits
  • Construction of electronic and ionic devices based on biological two-dimensional materials
  • Development of flexible devices using organic transistors
Fig.1 high-throughput sensor for drug side effects
Fig.2 Reconstruction of neuronal circuits using living cells
Fig.3 p+-i-p+ type organic field-effect transistor using conductive polymers

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